Publications

2025

1. Carra S, Zhang H, Kurukulaaratchy RJ, Arshad SH. Natural history of bronchial hyperresponsiveness and its association with asthma traits. Allergy. Accepted.
2. Chen S, Holloway JW, Karmaus W, Zhang H, Arshad SH, Ewart S. Trends in DNA Methylation over Time Between Parous and Nulliparous Young Women. Epigenomes. 2025 Jul 10;9(3):24. PMID: 40700040; PMCID: PMC12286171.doi: 10.3390/epigenomes9030024.
3. Farhan AJ, Kothalawala DM, Kurukulaaratchy RJ, Granell R, Simpson A, Murray C, Custovic A, Roberts G, Zhang H, Arshad SH. Response to correspondence: Prediction of adult asthma risk in early childhood using novel adult asthma predictive risk scores. Allergy. 2025 May;80(5):1554-1556. PMID: 38348787.doi: 10.1111/all.16059.
4. Neumann A, Sammallahti S, Cosin-Tomas M, Reese SE, Suderman M, Alemany S, Almqvist C, Andrusaityte S, Arshad SH, Bakermans-Kranenburg MJ, Beilin L, Breton C, Bustamante M, Czamara D, Dabelea D, Eng C, Eskenazi B, Fuemmeler BF, Gilliland FD, Grazuleviciene R, Håberg SE, Herberth G, Holland N, Hough A, Hu D, Huen K, Hüls A, Jarvelin MR, Jin J, Julvez J, Koletzko BV, Koppelman GH, Kull I, Lu X, Maitre L, Mason D, Melén E, Merid SK, Molloy PL, Mori TA, Mulder RH, Page CM, Richmond RC, Röder S, Ross JP, Schellhas L, Sebert S, Sheppard D, Snieder H, Starling AP, Stein DJ, Tindula G, van IJzendoorn MH, Vonk J, Walton E, Witonsky J, Xu CJ, Yang IV, Yousefi PD, Zar HJ, Zenclussen AC, Zhang H, Tiemeier H, London SJ, Felix JF, Cecil C. Epigenetic timing effects on child developmental outcomes: a longitudinal meta-regression of findings from the Pregnancy And Childhood Epigenetics Consortium. Genome Med. 2025 Apr 14;17(1):39. PMID: 40229801; PMCID: PMC11995515.doi: 10.1186/s13073-025-01451-7.
5. Zhang H, Duan J, Han L, Alam N, Ray M, Yang F, Jiang Y, Ewart S, Holloway JW, Karmaus W, Wang SL, Arshad SH. DNA methylation at birth and IgE trajectories from birth to adolescence, different patterns between White and Asian. Epigenomics. 2025 Mar;17(4):213-222. PMID: 39825623; PMCID: PMC11853557.doi: 10.1080/17501911.2025.2453412.
6. Melaram R, Zhang H, Adefisoye J, Arshad H. The Association of Childhood Allergic Diseases with Prenatal Exposure to Pollen Grains Through At-Birth DNA Methylation. Epigenomes. 2025 Mar 11;9(1):9. PMID: 40136322; PMCID: PMC11940834.doi: 10.3390/epigenomes9010009.
7. Warden DE, Zhang H, Jiang Y, Arshad HS, Karmaus W. The role of wheezing subtypes in the development of early childhood asthma. Respir Res. 2025 Feb 28;26(1):79. PMID: 40022143; PMCID: PMC11871585.doi: 10.1186/s12931-025-03153-5.
8. Mukhopadhyay A, Haque Mondol M, Rahman M, Unicomb L, Khan R, Mazumder H, Nahian Ferdous M, Pickering EV, Makris KC, Caban-Martinez AJ, Ahmed F, Shamsudduha M, Mzayek F, Jia C, Zhang H, Musah A, Fleming LE, Smeltzer MP, Chang HH, Jefferies JL, Kovesdy CP, Mou X, Mohd Naser A. The direct and urinary electrolyte-mediated effects of ambient temperature on population blood pressure: A causal mediation analysis. Environ Int. 2025 Jan;195:109208. PMID: 39705978; PMCID: PMC11757155.doi: 10.1016/j.envint.2024.109208.

Statistical Methods

1. Mou X, Zhang H, Arshad SH. Generalized Bayesian kernel machine regression. Stat Methods Med Res. 2025 Feb;34(2):243-257. PMID: 39668593.doi: 10.1177/09622802241280784 .

2024

1. Carra S, Zhang H, Tanno LK, Arshad SH, Kurukulaaratchy RJ. Adult Outcomes of Childhood Wheezing Phenotypes Are Associated with Early-Life Factors. J Pers Med. 2024 Dec 22;14(12):1171. PMID: 39728083; PMCID: PMC11677713.doi: 10.3390/jpm14121171.
2. Wang S, Casey E, Sordillo J, Aguilar-Lacasaña S, Morales Berstein F, Biedrzycki RJ, Brescianini S, Chen S, Hough A, Isaevska E, Kim WJ, Lecorguillé M, Li SS, Page CM, Park J, Röder S, Salontaji K, Santorelli G, Sun Y, Won S, Zillich E, Zillich L, Annesi-Maesano I, Arshad SH, Bustamante M, Cecil CAM, Elliott HR, Ewart S, Felix JF, Gagliardi L, Håberg SE, Herberth G, Heude B, Holloway JW, Huels A, Karmaus W, Koppelman GH, London SJ, Mumford SL, Nisticò L, Popovic M, Rusconi F, Schisterman EF, Stein DJ, Send T, Tiemeier H, Vonk JM, Vrijheid M, Wiemels JL, Witt SH, Wright J, Yeung EH, Zar HJ, Zenclussen AC, Zhang H, Chavarro JE, Hivert MF. Cesarean delivery and blood DNA methylation at birth and childhood: Meta-analysis in the Pregnancy and Childhood Epigenetics Consortium. Sci Adv. 2024 Nov 29;10(48):eadr2084. PMID: 39602535; PMCID: PMC11601205.doi: 10.1126/sciadv.adr2084.
3. Taylor ML, Alle M, Wilson R Jr, Rodriguez-Nieves A, Lutey MA, Slavney WF, Stewart J, Williams H, Amrhein K, Zhang H, Wang Y, Hoang TB, Huang X. Single Vesicle Surface Protein Profiling and Machine Learning-Based Dual Image Analysis for Breast Cancer Detection. Nanomaterials (Basel). 2024 Oct 30;14(21):1739. PMID: 39513819; PMCID: PMC11548014.doi: 10.3390/nano14211739.
4. Melaram R, Adefisoye J, Warden DE, Potter S, Arshad H, Zhang H. Pollen exposures in pregnancy and early life are associated with childhood asthma incidence. World Allergy Organ J. 2024 Oct 5;17(10):100976. PMID: 39435152; PMCID: PMC11491945.doi: 10.1016/j.waojou.2024.100976.
5. Abrar MNF, Zhang H, Jiang Y. Suggested guidelines in reporting results from mediation analysis, standardized or unstandardized? PLoS One. 2024 Sep 18;19(9):e0310429. PMID: 39292656; PMCID: PMC11410225.doi: 10.1371/journal.pone.0310429.
6. Jiang Y, Zhang H, Chen S, Ewart S, Holloway JW, Arshad H, Karmaus W. Intergenerational association of DNA methylation between parents and offspring. Sci Rep. 2024 Aug 27;14(1):19812. PMID: 39191877; PMCID: PMC11349889.doi: 10.1038/s41598-024-69317-3.
7. Ahn S, Kim S, Zhang H, Dobalian A, Slavich GM. Lifetime adversity predicts depression, anxiety, and cognitive impairment in a nationally representative sample of older adults in the United States. J Clin Psychol. 2024 May;80(5):1031-1049. PMID: 38294127; PMCID: PMC11216061.doi: 10.1002/jclp.23642.
8. Bunyavanich S, Becker PM, Altman MC, Lasky-Su J, Ober C, Zengler K, Berdyshev E, Bonneau R, Chatila T, Chatterjee N, Chung KF, Cutcliffe C, Davidson W, Dong G, Fang G, Fulkerson P, Himes BE, Liang L, Mathias RA, Ogino S, Petrosino J, Price ND, Schadt E, Schofield J, Seibold MA, Steen H, Wheatley L, Zhang H, Togias A, Hasegawa K. Analytical challenges in omics research on asthma and allergy: A National Institute of Allergy and Infectious Diseases workshop. J Allergy Clin Immunol. 2024 Apr;153(4):954-968. PMID: 38295882; PMCID: PMC10999353.doi: 10.1016/j.jaci.2024.01.014.
9. Freeman A, Abraham S, Kadalayil L, Varkonyi-Sepp J, Ainsworth B, Hudson-Colby JJ, Barber C, Dennison P, Azim A, Mistry H, Howarth P, Djukanovic R, Zhang H, Arshad SH, Haitchi HM, Kurukulaaratchy RJ. Associations of Breathing Pattern Disorder and Nijmegen Score With Clinical Outcomes in Difficult-to-Treat Asthma. J Allergy Clin Immunol Pract. 2024 Apr;12(4):938-947.e6. PMID: 38036249.doi: 10.1016/j.jaip.2023.11.036.
10. Mazumder H, Mondol MH, Rahman M, Khan R, Doza S, Unicomb L, Jahan F, Mukhopadhyay A, Makris KC, Caban-Martinez A, Iqbal R, Ahmed F, Creencia L, Shamsudduha M, Mzayek F, Jia C, Zhang H, Musah A, Fleming LE, Mou X, Kovesdy CP, Gribble MO, Naser AM. Sex-Specific Association of Ambient Temperature With Urine Biomarkers in Southwest Coastal Bangladesh. Kidney Int Rep. 2024 Mar 11;9(6):1860-1875. PMID: 38899224; PMCID: PMC11184407.doi: 10.1016/j.ekir.2024.03.002.
11. Abrar MNF, Jiang Y, Zhang H, Li L, Arshad H. Epigenetic Features in Newborns Associated with Preadolescence Lung Function and Asthma Acquisition during Adolescence. Epigenomes. 2024 Mar 22;8(2):12. PMID: 38525738; PMCID: PMC10961756.doi: 10.3390/epigenomes8020012.
12. Burch JB, Delage AF, Zhang H, McLain AC, Ray MA, Miller A, Adams SA, Hébert JR. Sleep disorders and cancer incidence: examining duration and severity of diagnosis among veterans. Front Oncol. 2024 Feb 26;14:1336487. PMID: 38469244; PMCID: PMC10927008.doi: 10.3389/fonc.2024.1336487.

Statistical Methods

1. Huang X, Zhang H. Detecting responsible nodes in differential Bayesian networks. Stat Med. 2024 Jul 30;43(17):3294-3312. PMID: 38831542.doi: 10.1002/sim.10125.
2. Wu C, Mou X, Zhang H. Gbdmr: identifying differentially methylated CpG regions in the human genome via generalized beta regressions. BMC Bioinformatics. 2024 Mar 5;25(1):97. PMID: 38443825; PMCID: PMC10916021.doi: 10.1186/s12859-024-05711-y.